Entity Central Index Key
Available for sale debt securities accumulated gross unrealized gain before tax, current.
Available for sale debt securities accumulated gross unrealized loss before tax current.
Cover [Abstract]
Document Type
Document Type
Amendment Flag
Amendment Flag
Document Period End Date
Document Period End Date
Document Fiscal Period Focus
Document Fiscal Period Focus
Document Fiscal Year Focus
Document Fiscal Year Focus
Trading Symbol
Trading Symbol
Entity Registrant Name
Entity Registrant Name
Entity Central Index Key
Current Fiscal Year End Date
Current Fiscal Year End Date
Entity Filer Category
Entity Filer Category
Entity File Number
Entity File Number
Entity Tax Identification Number
Entity Tax Identification Number
Entity Address, Address Line One
Entity Address Address Line1
Entity Address, City or Town
Entity Address City Or Town
Entity Address, State or Province
Entity Address State Or Province
Entity Address, Postal Zip Code
Entity Address Postal Zip Code
City Area Code
City Area Code
Local Phone Number
Local Phone Number
Entity Incorporation, State or Country Code
Entity Incorporation State Country Code
Entity Interactive Data Current
Entity Interactive Data Current
Document Annual Report
Document Annual Report
Document Transition Report
Document Transition Report
Title of 12(b) Security
Security12b Title
Security Exchange Name
Security Exchange Name
Entity Well-known Seasoned Issuer
Entity Well Known Seasoned Issuer
Entity Current Reporting Status
Entity Current Reporting Status
Entity Voluntary Filers
Entity Voluntary Filers
Entity Small Business
Entity Small Business
Entity Emerging Growth Company
Entity Emerging Growth Company
Entity Shell Company
Entity Shell Company
ICFR Auditor Attestation Flag
Icfr Auditor Attestation Flag
Entity Common Stock, Shares Outstanding
Entity Common Stock Shares Outstanding
Entity Public Float
Entity Public Float
Liability related to sale of future royalties.
Statement Of Financial Position [Abstract]
Assets
Assets [Abstract]
Current assets:
Assets Current [Abstract]
Cash and cash equivalents
Cash And Cash Equivalents At Carrying Value
Marketable securities
Marketable Securities Current
Prepaid expenses and other current assets
Prepaid Expense And Other Assets Current
Total current assets
Assets Current
Marketable securities
Marketable Securities Noncurrent
Restricted cash
Restricted Cash Noncurrent
Property and equipment, net
Property Plant And Equipment Net
Operating lease right-of-use asset
Operating Lease Right Of Use Asset
Other assets
Other Assets Noncurrent
Total assets
Assets
Liabilities and stockholders’ equity
Liabilities And Stockholders Equity [Abstract]
Current liabilities:
Liabilities Current [Abstract]
Accounts payable
Accounts Payable Current
Accrued and other current liabilities
Accrued Liabilities Current
Operating lease liability
Operating Lease Liability Current
Total current liabilities
Liabilities Current
Operating lease liability, net of current portion
Operating Lease Liability Noncurrent
Liability related to sale of future royalties
Liability Related To Sale Of Future Royalties
Other liabilities
Other Liabilities Noncurrent
Total liabilities
Liabilities
Commitments and contingencies (Note 7)
Commitments And Contingencies
Stockholders’ equity:
Stockholders Equity [Abstract]
Preferred stock, $0.0001 par value, 10,000,000 shares authorized; 0 shares issued and outstanding at December 31, 2020 and 2019
Preferred Stock Value
Common stock, $0.0001 par value, 490,000,000 shares authorized at December 31, 2020 and 2019; 51,112,302 and 44,413,404 shares issued and outstanding at December 31, 2020 and 2019, respectively
Common Stock Value
Additional paid-in capital
Additional Paid In Capital Common Stock
Accumulated other comprehensive income
Accumulated Other Comprehensive Income Loss Net Of Tax
Accumulated deficit
Retained Earnings Accumulated Deficit
Total stockholders’ equity
Stockholders Equity
Total liabilities and stockholders’ equity
Liabilities And Stockholders Equity
Preferred stock, par value
Preferred Stock Par Or Stated Value Per Share
Preferred stock, shares authorized
Preferred Stock Shares Authorized
Preferred Stock, shares issued
Preferred Stock Shares Issued
Preferred Stock, shares outstanding
Preferred Stock Shares Outstanding
Common stock, par value
Common Stock Par Or Stated Value Per Share
Common stock, shares authorized
Common Stock Shares Authorized
Common stock, shares issued
Common Stock Shares Issued
Common stock, shares outstanding
Common Stock Shares Outstanding
Income Statement [Abstract]
Operating expenses
Operating Expenses [Abstract]
Research and development
Research And Development Expense
General and administrative
General And Administrative Expense
Total operating expenses
Operating Expenses
Loss from operations
Operating Income Loss
Interest income
Investment Income Interest
Interest expense (includes $nil, $nil and $3,030 attributable to related parties for the years ended December 31, 2020, 2019 and 2018, respectively)
Interest Expense
Other income (expense), net (includes $49, $nil, and $2,736 expenses attributable to related parties for the years ended December 31, 2020, 2019, and 2018, respectively)
Other Nonoperating Income Expense
Loss on extinguishment of debt (includes $1,587 attributable to related parties for the year ended December 31, 2018)
Gains Losses On Extinguishment Of Debt
Net loss
Net Income Loss
Net loss per common share, basic and diluted
Earnings Per Share Basic And Diluted
Weighted-average common shares outstanding used in computing net loss per common share, basic and diluted
Weighted Average Number Of Share Outstanding Basic And Diluted
Other comprehensive income
Other Comprehensive Income Loss Net Of Tax Portion Attributable To Parent [Abstract]
Change in unrealized gains related to available-for-sale debt securities, net of tax
Other Comprehensive Income Availableforsale Securities Adjustment Net Of Tax Portion Attributable To Parent
Total other comprehensive income
Other Comprehensive Income Loss Net Of Tax Portion Attributable To Parent
Comprehensive loss
Comprehensive Income Net Of Tax
Amount of income (expense) related to non operating activities, classified as other attributable to related parties.
Loss on extinguishment of debt attributable to related parties.
Interest expense attributable to related parties
Interest Expense Related Party
Other income (expense) attributable to related parties
Other Non Operating Income Expense Attributable To Related Parties
Loss on extinguishment of debt attributable to related parties
Loss On Extinguishment Of Debt Attributable To Related Parties
Common stock issued upon conversion of preferred stock, shares.
Common stock issued upon conversion of preferred stock, value.
Conversion of redeemable convertible preferred stock warrant into common stock Warrants.
Issuance of common stock upon exercise of common stock warrants.
Issuance of common stock upon exercise of common stock warrants, shares.
Common stock issued upon conversion of convertible notes, value.
Common stock issued upon conversion of convertible notes, shares.
Vesting of restricted stock units, net of taxes withheld.
Vesting of restricted stock units net of taxes withheld shares.
Statement Of Stockholders Equity [Abstract]
Statement [Table]
Statement [Table]
Equity Components
Statement Equity Components [Axis]
Equity Component
Equity Component [Domain]
Common Stock
Common Stock [Member]
Additional Paid-In Capital
Additional Paid In Capital [Member]
Accumulated Other Comprehensive Income
Accumulated Other Comprehensive Income [Member]
Accumulated Deficit
Retained Earnings [Member]
Class of Stock
Statement Class Of Stock [Axis]
Class of Stock
Class Of Stock [Domain]
Redeemable Convertible Preferred Stock
Redeemable Convertible Preferred Stock [Member]
Statement [Line Items]
Statement [Line Items]
Beginning Balance
Redeemable convertible preferred stock, shares outstanding, beginning balance
Temporary Equity Shares Outstanding
Redeemable convertible preferred stock, beginning balance
Temporary Equity Carrying Amount Attributable To Parent
Beginning balance, shares
Shares Outstanding
Issuance of common stock upon exercise of stock options
Stock Issued During Period Value Stock Options Exercised
Issuance of common stock upon exercise of stock options, shares
Stock Issued During Period Shares Stock Options Exercised
Issuance of restricted stock awards
Stock Issued During Period Value Restricted Stock Award Net Of Forfeitures
Issuance of restricted stock awards, shares
Stock Issued During Period Shares Restricted Stock Award Net Of Forfeitures
Vesting of restricted stock units, net of taxes withheld
Vesting Of Restricted Stock Units Net Of Taxes Withheld
Vesting of restricted stock units, net of taxes withheld, shares
Vesting Of Restricted Stock Units Net Of Taxes Withheld Shares
Conversion of redeemable convertible preferred stock into common stock
Stock Issued During Period Value Conversion Of Convertible Securities
Conversion of redeemable convertible preferred stock into common stock, shares
Common Stock Issued Upon Conversion Of Preferred Stock Shares
Conversion of redeemable convertible preferred stock into common stock
Common Stock Issued Upon Conversion Of Preferred Stock Value
Conversion of redeemable convertible preferred stock into common stock, shares
Stock Issued During Period Shares Conversion Of Convertible Securities
Conversion of redeemable convertible preferred stock warrants into common stock warrants
Conversion Of Redeemable Convertible Preferred Stock Warrant Into Common Stock Warrants
Issuance of common stock upon exercise of common stock warrants
Issuance Of Common Stock Upon Exercise Of Common Stock Warrants
Issuance of common stock upon exercise of common stock warrants, shares
Issuance Of Common Stock Upon Exercise Of Common Stock Warrants Shares
Conversion of 2017 and 2018 convertible notes into common stock
Common Stock Issued Upon Conversion Of Convertible Notes Value
Conversion of 2017 and 2018 convertible notes into common stock, shares
Common Stock Issued Upon Conversion Of Convertible Notes Shares
Issuance of common stock in connection with initial public offering/follow-on offering, net of offering costs
Stock Issued During Period Value New Issues
Issuance of common stock in connection with initial public offering/follow-on offering, net of offering costs, shares
Stock Issued During Period Shares New Issues
Stock-based compensation expense
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
Other comprehensive income
Net loss
Ending Balance
Redeemable convertible preferred stock, shares outstanding, ending balance
Redeemable convertible preferred stock, ending balance
Ending balance, shares
Payments of offering costs on issuance of common stock in connection with initial public offering or follow on offering.
Offering costs with respect to issuance of common stock in connection with initial public offering/follow-on offering
Payments Of Offering Costs On Issuance Of Common Stock In Connection With Initial Public Offering Or Follow On Offering
Change in fair value of redeemable convertible preferred stock warrant liability.
Change in fair value of embedded derivative liability.
Operating lease right of use asset amortization.
Amortization of issuance costs.
Increase decrease in operating lease liability.
Deposits on property and equipment.
Proceeds from sale of future royalties, net of issuance costs.
Principal payments of tenant improvement allowance payable.
Unpaid offering costs.
Issuance of embedded derivative in connection to convertible notes.
Statement Of Cash Flows [Abstract]
Cash flows from operating activities
Net Cash Provided By Used In Operating Activities [Abstract]
Adjustments to reconcile net loss to net cash used in operating activities:
Adjustments To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities [Abstract]
Depreciation
Depreciation
Non-cash interest expense and amortization of debt discount and issuance cost
Amortization Of Financing Costs And Discounts
Change in fair value of redeemable convertible preferred stock warrant liability
Change In Fair Value Of Redeemable Convertible Preferred Stock Warrant Liability
Change in fair value of derivative instrument
Change In Fair Value Of Embedded Derivative Liability
Extinguishment of debt
Stock-based compensation
Share Based Compensation
Amortization (accretion) of premium (discount) on marketable securities
Accretion Amortization Of Discounts And Premiums Investments
Amortization of operating lease right-of-use asset
Operating Lease Right Of Use Asset Amortization
Amortization of issuance costs
Amortization Of Issuance Costs
Changes in assets and liabilities:
Increase Decrease In Operating Capital [Abstract]
Prepaid expense and other current assets
Increase Decrease In Prepaid Deferred Expense And Other Assets
Other assets
Increase Decrease In Other Operating Assets
Accounts payable
Increase Decrease In Accounts Payable
Accrued and other current liabilities
Increase Decrease In Accrued Liabilities And Other Operating Liabilities
Operating lease liability
Increase Decrease In Operating Lease Liability
Other liabilities
Increase Decrease In Other Operating Liabilities
Net cash used in operating activities
Net Cash Provided By Used In Operating Activities
Cash flows from investing activities
Net Cash Provided By Used In Investing Activities [Abstract]
Purchase of property and equipment
Payments To Acquire Property Plant And Equipment
Deposits on property and equipment
Deposits On Property And Equipment
Purchases of marketable securities
Payments To Acquire Marketable Securities
Maturities of marketable securities
Proceeds From Sale And Maturity Of Marketable Securities
Net cash provided by (used in) investing activities
Net Cash Provided By Used In Investing Activities
Cash flows from financing activities
Net Cash Provided By Used In Financing Activities [Abstract]
Proceeds from issuance of common stock in connection with offering, net of offering costs
Proceeds From Issuance Of Common Stock
Proceeds from issuance of common stock upon option exercise
Proceeds From Stock Options Exercised
Payments for restricted stock units, net of taxes withheld
Payments Related To Tax Withholding For Share Based Compensation
Proceeds from issuance of convertible notes (includes $9,560 from related parties for the years ended December 31, 2018)
Proceeds From Notes Payable
Debt issuance cost
Payments Of Debt Issuance Costs
Proceeds from sale of future royalties, net of issuance costs
Proceeds From Sale Of Future Royalties Net Of Issuance Costs
Principal payments of capital lease
Repayments Of Debt And Capital Lease Obligations
Principal payments of tenant improvement allowance payable
Principal Payments Of Tenant Improvement Allowance Payable
Net cash provided by financing activities
Net Cash Provided By Used In Financing Activities
Net increase in cash, cash equivalents and restricted cash
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Excluding Exchange Rate Effect
Cash, cash equivalents and restricted cash, at beginning of year
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
Cash, cash equivalents and restricted cash, at end of year
Reconciliation of cash, cash equivalents and restricted cash to consolidated balance sheets
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents [Abstract]
Supplemental cash flow information:
Supplemental Cash Flow Information [Abstract]
Cash paid for interest
Interest Paid Net
Supplemental disclosures of non-cash investing and financing information:
Cash Flow Noncash Investing And Financing Activities Disclosure [Abstract]
Operating lease right-of-use asset obtained in exchange for operating lease liability
Right Of Use Asset Obtained In Exchange For Operating Lease Liability
Purchase of property and equipment under accounts payable
Noncash Or Part Noncash Acquisition Fixed Assets Acquired1
Unpaid offering costs
Unpaid Offering Costs
Offering costs paid in restricted stock awards
Debt Issuance Costs Incurred During Noncash Or Partial Noncash Transaction
Derivative instrument related to convertible notes
Issuance Of Embedded Derivative
The cash inflow from issuance of convertible notes to related parties.
Proceeds from issuance of convertible notes
Proceeds From Issuance Of Convertible Notes To Related Parties
Documents Incorporated by Reference
Documents Incorporated By Reference [Text Block]
The entire disclosure for the company.
Organization Consolidation And Presentation Of Financial Statements [Abstract]
The Company
The Company [Text Block]
Accounting Policies [Abstract]
Summary of Significant Accounting Policies
Significant Accounting Policies [Text Block]
Property Plant And Equipment [Abstract]
Property and Equipment, net
Property Plant And Equipment Disclosure [Text Block]
Accounts Payable And Accrued Liabilities Current [Abstract]
Accrued Liabilities and Other Current Liabilities
Accounts Payable Accrued Liabilities And Other Liabilities Disclosure Current [Text Block]
Fair Value Disclosures [Abstract]
Fair Value Measurements
Fair Value Disclosures [Text Block]
Investments Debt And Equity Securities [Abstract]
Marketable Securities
Investments In Debt And Marketable Equity Securities And Certain Trading Assets Disclosure [Text Block]
Commitments And Contingencies Disclosure [Abstract]
Commitments and Contingencies
Commitments And Contingencies Disclosure [Text Block]
Income Tax Disclosure [Abstract]
Income Taxes
Income Tax Disclosure [Text Block]
Equity [Abstract]
Preferred Stock
Preferred Stock [Text Block]
Common Stock
Stockholders Equity Note Disclosure [Text Block]
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]
Stock-Based Compensation
Disclosure Of Compensation Related Costs Share Based Payments [Text Block]
Earnings Per Share [Abstract]
Net Loss per Share Attributable to Common Stockholders
Earnings Per Share [Text Block]
Compensation And Retirement Disclosure [Abstract]
401(k) plan
Pension And Other Postretirement Benefits Disclosure [Text Block]
Liability related to sale of future royalties.
Liability related to sale of future royalties.
Liability Related To Sale Of Future Royalties [Abstract]
Liability related to Sale of Future Royalties
Liability Related To Sale Of Future Royalties [Text Block]
Quarterly Financial Information Disclosure [Abstract]
Selected Quarterly Financial Data (Unaudited)
Quarterly Financial Information [Text Block]
Basis of Presentation
Basis Of Accounting Policy Policy [Text Block]
Reclassification
Prior Period Reclassification Adjustment Description
Principles of Consolidation
Consolidation Policy [Text Block]
Segments
Segment Reporting Policy Policy [Text Block]
Use of Estimates
Use Of Estimates
Risk and uncertainties.
Risk and Uncertainties
Risk And Uncertainties Policy [Text Block]
Concentration of Credit Risk
Concentration Risk Credit Risk
Cash and Cash Equivalents
Cash And Cash Equivalents Policy [Text Block]
Marketable Securities
Marketable Securities Policy
Restricted Cash
Cash And Cash Equivalents Restricted Cash And Cash Equivalents Policy
Fair Value Measurements
Fair Value Of Financial Instruments Policy
Leases
Lessee Leases Policy [Text Block]
Property and Equipment, Net
Property Plant And Equipment Policy [Text Block]
Impairment of Long-Lived Assets
Impairment Or Disposal Of Long Lived Assets Policy [Text Block]
Research and Development Expenses
Research And Development Expense Policy
Accrued research and development.
Accrued Research And Development
Accrued Research And Development Policy [Text Block]
Stock-Based Compensation
Share Based Compensation Option And Incentive Plans Policy
Income Taxes
Income Tax Policy [Text Block]
Comprehensive Loss
Comprehensive Income Policy Policy [Text Block]
Liability related to sale of future royalties.
Liability related to Sale of Future Royalties
Liability Related To Sale Of Future Royalties Policy [Text Block]
Credit Losses – Available-for-Sale Debt Securities
Credit Loss Financial Instrument Policy [Text Block]
Net Loss per Share Attributable to Common Stockholders
Earnings Per Share Policy [Text Block]
Recent Accounting Pronouncements
New Accounting Pronouncements Policy Policy [Text Block]
Summary of Property and Equipment, net
Property Plant And Equipment [Text Block]
Schedule of accrued liabilities and other current liabilities.
Schedule of Accrued Liabilities and Other Current Liabilities
Schedule Of Accrued Liabilities And Other Current Liabilities Table [Text Block]
Summary of Fair Value Hierarchy for Assets and Liabilities Measured at Fair Value on Recurring Basis
Schedule Of Fair Value Assets And Liabilities Measured On Recurring Basis Table [Text Block]
Summary of Marketable Securities Held
Marketable Securities [Text Block]
Summary of Maturities of Operating Lease Liabilities
Lessee Operating Lease Liability Maturity Table [Text Block]
Summary of Lessee, Weighted Average Remaining Lease Term and Weighted Average Discount Rates
Lease Cost Table [Text Block]
Schedule of Provision (Benefit) for Income Taxes
Schedule Of Components Of Income Tax Expense Benefit Table [Text Block]
Components of Loss before Income Taxes
Schedule Of Income Before Income Tax Domestic And Foreign Table [Text Block]
Components of Deferred Tax Assets
Schedule Of Deferred Tax Assets And Liabilities Table [Text Block]
Schedule of Reconciliation of Effective Tax Rate to Statutory U.S. Federal Rate
Schedule Of Effective Income Tax Rate Reconciliation Table [Text Block]
Summary of Unrecognized Tax Benefits Amounts
Schedule Of Unrecognized Tax Benefits Roll Forward Table [Text Block]
Schedule of common stock reserved for future issuance.
Schedule of Common Stock Reserved for Future Issuances
Schedule Of Common Stock Reserved For Future Issuance Table [Text Block]
Summary of Stock Options Activity Under 2018 Plan and 2015 Plan
Schedule Of Share Based Compensation Stock Options Activity Table [Text Block]
Schedule of share-based payment award, employee stock options, valuation assumptions.
Fair Value of Employee Stock Options Estimated Using Weighted-average Assumptions
Schedule Of Share Based Payment Award Employee Stock Options Valuation Assumptions Table [Text Block]
Schedule of share-based payment award, non-employee stock options, valuation assumptions.
Fair Value of Non-Employee Stock Options Estimated Using Weighted-average Assumptions
Schedule Of Share Based Payment Award Non Employee Stock Options Valuation Assumptions Table [Text Block]
Summary of Restricted Shares
Schedule Of Sharebased Compensation Restricted Stock And Restricted Stock Units Activity Table [Text Block]
Schedule of share-based payment award, performance based awards and RSUs, valuation assumptions.
Fair Value of Performance Based Awards and RSUs Estimated Using Weighted-average Assumptions
Schedule Of Share Based Payment Award Performance Based Awards And R S Us Valuation Assumptions Table [Text Block]
Summary of Stock-based Compensation Classified in Condensed Consolidated Statements of Operations and Comprehensive Loss
Schedule Of Compensation Cost For Share Based Payment Arrangements Allocation Of Share Based Compensation Costs By Plan Table [Text Block]
Computation of Basic and Diluted Net Loss per Share Attributable to Common Stockholders
Schedule Of Earnings Per Share Basic And Diluted Table [Text Block]
Summary of Anti-dilutive Securities Excluded from Computation of Diluted Net Loss per Share
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Text Block]
Schedule of Quarterly Financial Information
Schedule Of Quarterly Financial Information Table [Text Block]
Gross proceeds from initial public offering.
Organization consolidation and presentation of financial statements.
Organization consolidation and presentation of financial statements.
Organization Consolidation And Presentation Of Financial Statements [Table]
Organization Consolidation And Presentation Of Financial Statements [Table]
Sale of Stock
Subsidiary Sale Of Stock [Axis]
Sale of Stock
Sale Of Stock Name Of Transaction [Domain]
Initial Public Offering
I P O [Member]
Class of Warrant or Right
Class Of Warrant Or Right [Axis]
Class of Warrant or Right
Class Of Warrant Or Right [Domain]
Warrant
Warrant [Member]
Stock Conversion Description
Conversion Of Stock By Unique Description [Axis]
Conversion of Stock, Name
Conversion Of Stock Name [Domain]
Warrants exercised into convertible preferred shares then Converted.
Warrants Exercised Into Convertible Preferred Shares Then Converted
Warrants Exercised Into Convertible Preferred Shares Then Converted [Member]
Long-term Debt, Type
Longterm Debt Type [Axis]
Long-term Debt, Type
Longterm Debt Type [Domain]
2017 convertible notes.
2017 Convertible Notes
Two Thousand Seventeen Convertible Notes [Member]
2018 convertible notes.
2018 Convertible Notes
Two Thousand Eighteen Convertible Notes [Member]
Follow-On Offering.
Follow-On Offering
Follow On Offering [Member]
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Stock issued during period
Share issued price, per share
Shares Issued Price Per Share
Gross proceeds from initial public offering
Gross Proceeds From Initial Public Offering
Net proceeds from initial public offering
Proceeds From Issuance Initial Public Offering
The number of shares of common stock issued from warrants exercised.
Conversion of redeemable convertible preferred stock warrants into common stock warrants shares.
Warrants exercised into common stock shares
Warrants Exercised
Conversion of preferred stock warrants into common stock warrants, shares
Conversion Of Redeemable Convertible Preferred Stock Warrants Into Common Stock Warrants Shares
Gross proceeds from issuance of common stock.
Gross proceeds from issuance of common stock
Gross Proceeds From Issuance Of Common Stock
Net proceeds from issuance of common stock
Summary of significant accounting policies.
Summary of significant accounting policies.
Summary Of Significant Accounting Policies [Table]
Summary Of Significant Accounting Policies [Table]
Statistical Measurement
Range [Axis]
Statistical Measurement
Range [Member]
Maximum
Maximum [Member]
Minimum
Minimum [Member]
Restricted Cash and Cash Equivalents
Restricted Cash And Cash Equivalents Cash And Cash Equivalents [Axis]
Cash and Cash Equivalents
Restricted Cash And Cash Equivalents Cash And Cash Equivalents [Member]
Deposited with Financial Institution
Bank Time Deposits [Member]
Long-Lived Tangible Asset
Property Plant And Equipment By Type [Axis]
Long-Lived Tangible Asset
Property Plant And Equipment Type [Domain]
Laboratory equipment.
Laboratory Equipment
Laboratory Equipment [Member]
Computer equipment and office equipment.
Computer Equipment and Office Equipment
Computer Equipment And Office Equipment [Member]
Computer Software
Software Development [Member]
Furniture and Fixtures
Furniture And Fixtures [Member]
Minimum
Related Party Transaction
Related Party Transaction [Axis]
Related Party Transaction
Related Party Transaction [Domain]
Baker bros advisors LP.
Baker Bros. Advisors LP
Baker Bros Advisors L P [Member]
Collaborative Arrangement and Arrangement Other than Collaborative
Type Of Arrangement [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative
Arrangements And Nonarrangement Transactions [Member]
Funding agreement.
Funding Agreement
Funding Agreement [Member]
Accounting Standards Update
Adjustments For New Accounting Pronouncements [Axis]
Accounting Standards Update
Type Of Adoption [Member]
Accounting Standards Update 2016-02
Accounting Standards Update201602 [Member]
ASU 2016-13
Accounting Standards Update201613 [Member]
Summary of Significant Accounting Policies [Line Items]
Summary Of Significant Accounting Policies [Line Items]
Foreign currency transaction loss
Foreign Currency Transaction Gain Loss Realized
Number of reportable segments
Number Of Reportable Segments
Number of operating segments
Number Of Operating Segments
Long-term restricted cash
Property and equipment estimated useful lives of assets
Property Plant And Equipment Useful Life
Impairment of long-lived assets
Impairment Of Long Lived Assets Held For Use
Unrecognized tax benefits, interest and penalties charged
Unrecognized Tax Benefits Income Tax Penalties And Interest Expense
Capped percentage of royalty on future net sales.
Related party transaction ownership percentage threshold.
Capped percentage of royalty on future net sales
Capped Percentage Of Royalty On Future Net Sales
Contractual obligation under funding agreement
Contractual Obligation
Ownership percentage threshold
Related Party Transaction Ownership Percentage Threshold
Derecognition of noncurrent deferred liabilities.
Operating lease liability
Operating Lease Liability
Derecognition of noncurrent deferred liabilities
Derecognition Of Noncurrent Deferred Liabilities
Allowance for credit losses for available-for-sale debt securities
Debt Securities Available For Sale Allowance For Credit Loss
Schedule Of Property Plant And Equipment [Table]
Schedule Of Property Plant And Equipment [Table]
Leasehold Improvement
Leasehold Improvements [Member]
Computer Hardware
Computer Equipment [Member]
Computer software.
Computer Software
Computer Software [Member]
Office Equipment
Office Equipment [Member]
Construction in Progress
Construction In Progress [Member]
Property Plant and Equipment [Line Items]
Property Plant And Equipment [Line Items]
Total property and equipment
Property Plant And Equipment Gross
Less: Accumulated depreciation
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
Property and equipment, net
Accrued clinical trial and related costs current.
Accrued research and development current.
Accrued legal fees current.
Accrued clinical trial and related costs
Accrued Clinical Trial And Related Costs Current
Accrued research and development
Accrued Research And Development Current
Accrued salaries and benefits
Employee Related Liabilities Current
Accrued legal fees
Accrued Legal Fees Current
Accrued professional fees
Accrued Professional Fees Current
Accrued other liabilities
Other Accrued Liabilities Current
Total accrued and other current liabilities
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Measurement Frequency
Fair Value By Measurement Frequency [Axis]
Measurement Frequency
Fair Value Measurement Frequency [Domain]
Fair Value, Measurements, Recurring
Fair Value Measurements Recurring [Member]
Fair Value Hierarchy and NAV
Fair Value By Fair Value Hierarchy Level [Axis]
Fair Value Hierarchy and NAV
Fair Value Measurements Fair Value Hierarchy [Domain]
Quoted Price in Active Markets (Level 1)
Fair Value Inputs Level1 [Member]
Significant Observable Inputs (Level 2)
Fair Value Inputs Level2 [Member]
Significant Unobservable Inputs (Level 3)
Fair Value Inputs Level3 [Member]
Asset Class
Fair Value By Asset Class [Axis]
Asset Class
Fair Value Assets Measured On Recurring Basis Unobservable Input Reconciliation By Asset Class [Domain]
Money Market Funds
Money Market Funds [Member]
U.S. Treasury Securities
U S Treasury Securities [Member]
Corporate Notes
Corporate Note Securities [Member]
Significant Unobservable Inputs (Level 3)
Repurchase agreement.
Repurchase Agreement
Repurchase Agreement [Member]
Commercial Paper
Commercial Paper [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Cash equivalents
Cash And Cash Equivalents Fair Value Disclosure
Marketable securities
Available For Sale Securities Debt Securities
Total
Assets Fair Value Disclosure
Transfers between hierarchy levels.
Recurring
Nonrecurring
Fair Value Measurements Nonrecurring [Member]
Liability measured at fair value
Fair Value Measurement With Unobservable Inputs Reconciliations Recurring Basis Liability Value
Transfers of assets or liabilities between the fair value measurement levels
Transfers Between Hierarchy Levels
Available for sale debt securities amortized cost basis current.
Available for sale securities amortized cost basis noncurrent.
Available for sale debt securities accumulated gross unrealized gain before tax non current.
Available for sale debt securities accumulated gross unrealized loss before tax non current.
Marketable Securities [Table]
Marketable Securities [Table]
Investment Type
Investment Type [Axis]
Investments
Investment Type Categorization [Member]
Marketable Securities [Line Items]
Marketable Securities [Line Items]
Amortized Cost, current
Available For Sale Debt Securities Amortized Cost Basis Current
Unrealized Gains, current
Available For Sale Debt Securities Accumulated Gross Unrealized Gain Before Tax Current
Unrealized Losses, current
Available For Sale Debt Securities Accumulated Gross Unrealized Loss Before Tax Current
Fair Value, current
Available For Sale Securities Debt Securities Current
Amortized Cost, noncurrent
Available For Sale Debt Securities Amortized Cost Basis Noncurrent
Unrealized Gains, noncurrent
Available For Sale Debt Securities Accumulated Gross Unrealized Gain Before Tax Non Current
Unrealized Losses, noncurrent
Available For Sale Debt Securities Accumulated Gross Unrealized Loss Before Tax Non Current
Fair Value, noncurrent
Available For Sale Securities Debt Securities Noncurrent
Marketable securities, contractual maturities
Debt Securities Available For Sale Term
Realized gains or losses recognized on sale or maturity of available-for-sale debt securities
Debt Securities Available For Sale Realized Gain Loss
Marketable securities with unrealized losses
Available For Sale Debt Securities Accumulated Gross Unrealized Loss Before Tax
Number of leased buildings.
Lessee operating lease initial term of contract.
Lessee operating lease monthly rent expense.
Annual rent year over year increase percentage.
Lessee operating lease rent abatement.
Tenant improvement allowance.
Cash-collateralized letter of credit.
Number of options to extend lease term.
Commitments and contingencies disclosure.
Commitments and contingencies disclosure.
Commitments And Contingencies Disclosure [Table]
Commitments And Contingencies Disclosure [Table]
Lease Contractual Term
Lease Contractual Term [Axis]
Lease Contractual Term
Lease Contractual Term [Domain]
Lease Agreement on June two thousand and twenty
Lease Agreement on June 2020
Lease Agreement On June Two Thousand And Twenty [Member]
Building one.
1200 Page Mill Road in Palo Alto
Building One [Member]
Building two.
1250 Page Mill Road in Palo Alto
Building Two [Member]
Geographical
Statement Geographical [Axis]
Geographical
Segment Geographical [Domain]
California
CALIFORNIA
Lease agreement on April two thousand and twenty.
Lease Agreement on April 2020
Lease Agreement On April Two Thousand And Twenty [Member]
Office and laboratory space.
Rottenstrasse 5 in Visp
Office And Laboratory Space [Member]
Switzerland
SWITZERLAND
Manufacturing agreement.
Manufacturing Agreement
Manufacturing Agreement [Member]
Clinical and commercial supply.
Clinical and Commercial Supply of Drug Substance
Clinical And Commercial Supply [Member]
Lease agreement on April and June two thousand and twenty
Lease Agreement on April and June 2020
Lease Agreement On April And June Two Thousand And Twenty [Member]
Counterparty Name
Counterparty Name [Axis]
Counterparty Name
Repurchase Agreement Counterparty Name [Domain]
Lonza.
Lonza
Lonza [Member]
Finite-Lived Intangible Assets by Major Class
Finite Lived Intangible Assets By Major Class [Axis]
Finite-Lived Intangible Assets, Major Class Name
Finite Lived Intangible Assets Major Class Name [Domain]
Service Agreements
Service Agreements [Member]
Purchase Commitment, Excluding Long-term Commitment
Purchase Commitment Excluding Longterm Commitment [Axis]
Purchase Commitment, Excluding Long-term Commitment
Purchase Commitment Excluding Longterm Commitment [Domain]
Purchase Commitments
Purchase Commitment [Member]
Cancellable Assignment and License Agreement
Licensing Agreements [Member]
Tenant improvement allowance agreement.
Tenant Improvement Allowance Agreement
Tenant Improvement Allowance Agreement [Member]
Leasehold Improvements
Debt Instrument
Debt Instrument [Axis]
Debt Instrument, Name
Debt Instrument Name [Domain]
Tenant improvement allowance payable.
Tenant Improvement Allowance Payable
Tenant Improvement Allowance Payable [Member]
Commitments And Contingencies Disclosure [Line Items]
Commitments And Contingencies Disclosure [Line Items]
Number of buildings leased
Number Of Leased Buildings
Lease area
Area Of Land
Initial lease term
Lessee Operating Lease Initial Term Of Contract
Monthly rent expense
Lessee Operating Lease Monthly Rent Expense
Annual rent year-over-year increase percentage
Annual Rent Year Over Year Increase Percentage
Total rent abatement
Lessee Operating Lease Rent Abatement
Lessee operating lease option to extend
Lessee Operating Lease Option To Extend
Tenant improvement allowance
Tenant Improvement Allowance
Number of options to extend lease term
Number Of Options To Extend Lease Term
Cash-collateralized letter of credit
Cash Collateralized Letter Of Credit
Automatic renewal interval.
Automatic renewal interval
Automatic Renewal Interval
Lessee, operating lease, term of contract
Lessee Operating Lease Term Of Contract
Operating Lease
Operating Lease Liabilities Payments Due [Abstract]
2021
Lessee Operating Lease Liability Payments Due Next Twelve Months
2022
Lessee Operating Lease Liability Payments Due Year Two
2023
Lessee Operating Lease Liability Payments Due Year Three
2024
Lessee Operating Lease Liability Payments Due Year Four
2025
Lessee Operating Lease Liability Payments Due Year Five
Thereafter
Lessee Operating Lease Liability Payments Due After Year Five
Total undiscounted lease payments
Lessee Operating Lease Liability Payments Due
Less: imputed interest
Lessee Operating Lease Liability Undiscounted Excess Amount
Total operating lease liabilities
Weighted-average remaining lease term (in years)
Operating Lease Weighted Average Remaining Lease Term1
Weighted-average discount rate
Operating Lease Weighted Average Discount Rate Percent
Estimated capital contributions.
Contractual obligation due in second year and after.
Manufacturing agreement initial term.
Manufacturing agreement term that can be extended.
Estimated capital contribution
Estimated Capital Contributions
Annual suite fees payment for 2021
Contractual Obligation Due In Next Twelve Months
Annual suite fees payment each year after 2021
Contractual Obligation Due In Second Year And After
Manufacturing agreement initial term
Manufacturing Agreement Initial Term
Manufacturing agreement term that can be extended
Manufacturing Agreement Term That Can Be Extended
Lease liabilities
Unrecorded unconditional purchase obligation cancellation fees.
Contractual obligation period.
Cancelable and/ or non-cancelable contractual obligations, total
Unrecorded Unconditional Purchase Obligation Balance Sheet Amount
Contractual obligation period
Contractual Obligation Period
Unrecorded unconditional purchase obligation, expenses recognized
Unrecorded Unconditional Purchase Obligation Purchases
Unrecorded unconditional purchase obligation, cancellation fees
Unrecorded Unconditional Purchase Obligation Cancellation Fees
Noncancellable purchase commitments, including potential cancellation fees.
Noncancellable purchase commitments, including potential cancellation fees
Noncancellable Purchase Commitments Including Potential Cancellation Fees
Milestone payments and royalties on net sales that are not estimable.
Milestone payments
Unrecorded Milestone And Royalty Payments
Improvements allowance payable to be drawn
Debt Instrument Face Amount
Interest rate
Debt Instrument Interest Rate Stated Percentage
Lease term
Lease Expiration Date1
Debt instrument term
Debt Instrument Term
Current portion of tenant improvement allowance payable
Other liabilities, non-current portion of tenant Improvement allowance payable
Current:
Current Income Tax Expense Benefit Continuing Operations [Abstract]
Federal
Current Federal Tax Expense Benefit
State
Current State And Local Tax Expense Benefit
Foreign
Current Foreign Tax Expense Benefit
Total current
Current Income Tax Expense Benefit
Deferred:
Deferred Income Tax Expense Benefit Continuing Operations [Abstract]
Federal
Deferred Federal Income Tax Expense Benefit
State
Deferred State And Local Income Tax Expense Benefit
Foreign
Deferred Foreign Income Tax Expense Benefit
Total deferred
Deferred Income Tax Expense Benefit
Provision (Benefit) for income taxes
Income Tax Expense Benefit
United States
Income Loss From Continuing Operations Before Income Taxes Domestic
Foreign
Income Loss From Continuing Operations Before Income Taxes Foreign
Total loss before income taxes
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
Deferred tax assets tax operating lease liability.
Deferred tax liabilities operating lease right-of-use asset.
Deferred tax liabilities capitalized legal fees.
Deferred tax assets:
Deferred Tax Assets Net [Abstract]
Net operating loss carryforwards
Deferred Tax Assets Operating Loss Carryforwards
Intangible assets
Deferred Tax Assets Goodwill And Intangible Assets
Research and development tax credits
Deferred Tax Assets Tax Credit Carryforwards Research
Stock-based compensation
Deferred Tax Assets Tax Deferred Expense Compensation And Benefits Share Based Compensation Cost
Accruals
Deferred Tax Assets Tax Deferred Expense Reserves And Accruals
Operating lease liability
Deferred Tax Assets Tax Operating Lease Liability
Property and equipment
Deferred Tax Assets Property Plant And Equipment
Total deferred tax assets
Deferred Tax Assets Gross
Valuation allowance
Deferred Tax Assets Valuation Allowance
Net deferred tax assets
Deferred Tax Assets Net
Deferred tax liabilities:
Deferred Tax Liabilities Net [Abstract]
Operating lease right-of-use asset
Deferred Tax Liabilities Operating Lease Right Of Use Asset
Capitalized legal fees
Deferred Tax Liabilities Capitalized Legal Fees
Total deferred tax liabilities
Deferred Income Tax Liabilities
Total net deferred tax assets
Deferred Tax Assets Liabilities Net
Income taxes.
Income taxes.
Income Taxes [Table]
Income Taxes [Table]
Income Tax Authority
Income Tax Authority [Axis]
Income Tax Authority
Income Tax Authority [Domain]
Federal
Domestic Country [Member]
State
State And Local Jurisdiction [Member]
Tax Credit Carryforward
Tax Credit Carryforward [Axis]
Tax Credit Carryforward, Name
Tax Credit Carryforward Name [Domain]
Net operating loss not subject to expiration.
Net Operating Loss Not Subject to Expiration
Net Operating Loss Not Subject To Expiration [Member]
California
California Franchise Tax Board [Member]
Income Taxes [Line Items]
Income Taxes [Line Items]
Increase in valuation allowance
Valuation Allowance Deferred Tax Asset Change In Amount
Operating loss carryforwards, expiration start year.
Net operating loss
Operating Loss Carryforwards
Net operating loss carryforwards expiration start year
Operating Loss Carryforwards Expiration Start Year
Research and development credit carryforwards expiration start year.
Research and development credit carryforwards expiration year description.
Research and development credit carryforwards
Tax credit carryforwards expiration start year
Research And Development Credit Carryforwards Expiration Start Year
Tax credit carryforward, expiration year
Research And Development Credit Carryforwards Expiration Year Description
Effective income tax rate reconciliation, sale of future royalties.
Effective income tax rate reconciliation fair value adjustments.
Effective income tax rate reconciliation extinguishment of convertible note.
Federal statutory income tax rate
Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
State taxes
Effective Income Tax Rate Reconciliation State And Local Income Taxes
Foreign tax rate differential
Effective Income Tax Rate Reconciliation Foreign Income Tax Rate Differential
Change in valuation allowance
Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
Stock-based compensation
Effective Income Tax Rate Reconciliation Nondeductible Expense Share Based Compensation Cost
Research tax credit
Effective Income Tax Rate Reconciliation Tax Credits Research
Other
Effective Income Tax Rate Reconciliation Other Adjustments
Sale of future royalties
Effective Income Tax Rate Reconciliation Sale Of Future Royalties
Section 162(m)
Effective Income Tax Rate Reconciliation Deductions
Fair value adjustments
Effective Income Tax Rate Reconciliation Fair Value Adjustments
Extinguishment of convertible note
Effective Income Tax Rate Reconciliation Extinguishment Of Convertible Note
Provision for income taxes
Effective Income Tax Rate Continuing Operations
Unrecognized tax benefits at beginning of period
Unrecognized Tax Benefits
Increases related to prior year tax positions
Unrecognized Tax Benefits Increases Resulting From Prior Period Tax Positions
Increases related to current year tax positions
Unrecognized Tax Benefits Increases Resulting From Current Period Tax Positions
Unrecognized tax benefits at end of period
Income tax examination, number of periods open for examination.
Number of periods open for examination
Income Tax Examination Number Of Periods Open For Examination
Schedule Of Stock By Class [Table]
Schedule Of Stock By Class [Table]
Class Of Stock [Line Items]
Class Of Stock [Line Items]
Common stock, number of votes per share.
Common stock, number of vote per share
Common Stock Number Of Votes Per Share
Warrant
Award Type
Award Type [Axis]
Award Type
Share Based Compensation Arrangements By Share Based Payment Award Award Type And Plan Name [Domain]
Stock options outstanding and release of restricted shares.
Stock Options Outstanding and Release of Restricted Shares
Stock Options Outstanding And Release Of Restricted Shares [Member]
Two thousand eighteen equity incentive plan.
2018 Equity Incentive Plan
Two Thousand Eighteen Equity Incentive Plan [Member]
Two thousand eighteen employee share purchase plan.
2018 Employee Share Purchase Plan
Two Thousand Eighteen Employee Share Purchase Plan [Member]
Common stock reserved for future issuances
Common Stock Capital Shares Reserved For Future Issuance
Share based compensation arrangement by share based payment award options outstanding period increase decrease percentage.
Exercise price must be equal to at least 110% of the fair market value of the common stock on the grant date.
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Plan Name
Plan Name [Axis]
Plan Name
Plan Name [Domain]
Incentive stock options.
Incentive Stock Options
Incentive Stock Options [Member]
Incentive stock options granted to a greater than 10% stockholder.
ISO Granted to a Greater than 10% Stockholder
Incentive Stock Options Granted To Greater Than Ten Percent Stockholder [Member]
Employee Stock Options
Employee Stock Option [Member]
Non-employee stock option.
Non-employee Stock Options
Non Employee Stock Option [Member]
Options granted to non employees.
Options Granted to Non-employees
Options Granted To Non Employees [Member]
Restricted Stock Awards (RSAs)
Restricted Stock [Member]
Restricted Stock Units (RSUs)
Restricted Stock Units R S U [Member]
Performance based equity awards.
Performance Based Equity Awards
Performance Based Equity Awards [Member]
Performance-based stock options.
Performance-based Stock Options
Performance Based Stock Options [Member]
Performance-based restricted stock unit.
Performance Based Restricted Stock Units
Performance Based Restricted Stock Unit [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Common stock, shares reserved for issuance
Share Based Compensation Arrangement By Share Based Payment Award Number Of Additional Shares Authorized
Number of shares increases annually
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Period Increase Decrease
Percentage of outstanding stock
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Period Increase Decrease Percentage
Options, periods granted
Sharebased Compensation Arrangement By Sharebased Payment Award Expiration Period
Options exercise price, percentage of estimated fair value of shares on grant date
Share Based Compensation Arrangement By Share Based Payment Award Exercise Price
Awards vesting period
Share Based Compensation Arrangement By Share Based Payment Award Award Requisite Service Period1
Number of shares available for grant
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant
Two thousand eighteen and two thousand fifteen equity incentive plan.
2018 Plan and 2015 Equity Incentive Plan
Two Thousand Eighteen And Two Thousand Fifteen Equity Incentive Plan [Member]
Number of Options
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Roll Forward
Beginning balance
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
Granted
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross
Exercised
Forfeited or canceled
Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures And Expirations In Period
Ending balance
Shares exercisable
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number
Vested and expected to vest
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Number
Weighted Average Exercise Price
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price Rollforward
Beginning balance
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
Granted
Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price
Exercised
Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price
Forfeited or canceled
Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures And Expirations In Period Weighted Average Exercise Price
Ending balance
Share-based compensation arrangement by share-based payment award, options, weighted average remaining contractual term.
Weighted Average Remaining Contractual Term (in years)
Share Based Compensation Arrangement By Share Based Payment Award Options Weighted Average Remaining Contractual Term [Abstract]
Weighted Average Remaining Contractual Term (in years)
Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2
Share-based compensation arrangement by share-based payment award, options, aggregate intrinsic value.
Aggregate Intrinsic Value
Share Based Compensation Arrangement By Share Based Payment Award Options Aggregate Intrinsic Value [Abstract]
Beginning balance
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
Stock options, weighted-average grant date fair value
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
Expected volatility
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate
Risk-free interest rate
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate
Dividend yield
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
Expected term
Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1
Dividends paid
Payments Of Dividends
Expected dividend payment
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Payments
Total fair value of employee options vested
Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested In Period Fair Value1
Stock-based compensation expense recognized
Allocated Share Based Compensation Expense
Stock options, granted
Number of Restricted Shares
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Roll Forward
Unvested, beginning balance
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Number
Granted
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period
Vested
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period
Shares withheld related to net share settlement of RSUs
Shares Paid For Tax Withholding For Share Based Compensation
Canceled
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeited In Period
Unvested, ending balance
Shares withheld related to net share settlement of RSUs weighted average grant date fair value
Weighted Average Grant Date Fair Value
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Weighted Average Grant Date Fair Value Roll Forward
Unvested, beginning balance
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Weighted Average Grant Date Fair Value
Granted
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period Weighted Average Grant Date Fair Value
Vested
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period Weighted Average Grant Date Fair Value
Shares withheld related to net share settlement of RSUs
Shares Withheld Related To Net Share Settlement Of R S Us Weighted Average Grant Date Fair Value
Canceled
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeitures Weighted Average Grant Date Fair Value
Unvested, ending balance
Stock-based compensation of total fair value vested
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period Total Fair Value
Stock units, granted
Share-based compensation arrangement by share-based payment award, award vesting description.
Vesting period
Share Based Compensation Arrangement By Share Based Payment Award Award Vesting Description
Awards vested
Weighted-average grant date fair value
Sharebased Compensation Arrangement By Sharebased Payment Award Options Nonvested Weighted Average Grant Date Fair Value
Weighted-average grant date fair value
Common stock, shares reserved for issuance
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Income Statement Location
Income Statement Location [Axis]
Income Statement Location
Income Statement Location [Domain]
Research and Development
Research And Development Expense [Member]
General and Administrative
General And Administrative Expense [Member]
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]
Total stock-based compensation
Unrecognized stock-based compensation expense
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Stock Options
Unrecognized stock-based compensation weighted-average period expected for recognition
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Period For Recognition1
Weighted average number of shares outstanding adjustment.
Earnings Per Share Basic And Diluted [Abstract]
Numerator:
Net Income Loss Available To Common Stockholders Basic [Abstract]
Denominator:
Weighted Average Number Of Shares Outstanding [Abstract]
Weighted-average shares outstanding
Weighted Average Number Of Shares Issued Basic
Less: weighted-average unvested restricted shares and shares subject to repurchase
Weighted Average Number Of Shares Outstanding Adjustment
Net loss per share attributable to common stockholders, basic and diluted
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Antidilutive Securities
Antidilutive Securities Excluded From Computation Of Earnings Per Share By Antidilutive Securities [Axis]
Antidilutive Securities, Name
Antidilutive Securities Name [Domain]
Unvested Restricted Shares
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Anti-dilutive securities excluded from the computation of diluted net loss per share
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
Defined contribution plan, employer matching contribution cap on employee contribution limit.
Defined Contribution Plan [Table]
Defined Contribution Plan [Table]
Income Tax Authority, Name
Income Tax Authority Name [Axis]
Income Tax Authority, Name
Income Tax Authority Name [Domain]
IRS
Internal Revenue Service I R S [Member]
Defined Contribution Plan Disclosure [Line Items]
Defined Contribution Plan Disclosure [Line Items]
Plan name
Description Of Defined Contribution Pension And Other Postretirement Plans
Defined Contribution Plan, Plan Name [Extensible List]
Defined Contribution Plan Plan Name Extensible List
Employer matching contribution, percent of match
Defined Contribution Plan Employer Matching Contribution Percent Of Match
Defined contribution plan, employer matching contribution cap on employee contribution limit
Defined Contribution Plan Employer Matching Contribution Cap On Employee Contribution Limit
Expense related to matching contributions
Defined Contribution Plan Cost Recognized
Related party transaction ownership percentage.
Percentage of repurchase of royalties.
Schedule Of Related Party Transactions By Related Party [Table]
Schedule Of Related Party Transactions By Related Party [Table]
Related Party Transaction [Line Items]
Related Party Transaction [Line Items]
Capped percentage of royalty on future net sales
Ownership percentage
Related Party Transaction Ownership Percentage
Percentage of repurchase of royalties
Percentage Of Repurchase Of Royalties
Funds payable upon enrollment of patients.
Percentage of patients to be enrolled.
Proceeds from sale of future royalties
Funds to be payable upon enrollment of patients
Funds Payable Upon Enrollment Of Patients
Percentage of patients to be enrolled
Percentage Of Patients To Be Enrolled
Interest expense, liability related to sale of future royalties.
Liability related to sale of future royalties
Interest expense, liability related to sale of future royalties
Interest Expense Liability Related To Sale Of Future Royalties